Keynote Speaking & Presentations
With humor, authenticity and vulnerability, I share valuable lessons on adaptation, resilience, optimism, gratitude and the power of a positive mindset. I demonstrate how reframing challenges as opportunities for growth and transformation can help everyone overcome even the most daunting circumstances. I encourage the audience to nurture their own resilience and discover their unique abilities to adapt and thrive in the face of adversity.
Keynote #1
Finding Your New 100%: Redefining Resilience When There Is No Comeback Story
What do you do when resilience isn’t about bouncing back – because back no longer exists?
We’ve been told resilience means recovery. Push through, come out stronger, find your way back to who you were. But for anyone navigating chronic illness, irreversible change, or circumstances that don’t resolve – that definition fails them at the moment they need it most.
Lindsy Matthews knows this firsthand. Living with incurable Stage 4 metastatic breast cancer while continuing to thrive as a keynote speaker, University of Toronto instructor, and mother of two, Lindsy has built a new framework for resilience – one that doesn’t require a happy ending to count as success.
In this deeply honest and surprisingly joyful keynote – which became the foundation of Lindsy’s second TEDx talk – audiences discover how to stop measuring themselves against who they used to be, how to find genuine forward momentum even when the path has fundamentally changed, and why accepting a new version of your “100%” isn’t giving up – it’s the most courageous thing you can do.
Delivered with warmth, humour, and unflinching honesty, this talk leaves audiences with both emotional resonance and practical tools they can apply immediately – at work and in life.
Ideal for: leadership and wellness events, healthcare and pharmaceutical conferences, cancer awareness galas, women’s leadership programs, and any audience navigating significant organizational or personal change.
Suggested Length: 45-60 minutes (including 15 minutes Q&A)
Keynote #2
The Future Self Perspective: How to Use Tomorrow to Transform Today
Most of us try to manage the present by focusing harder on the present. Lindsy Matthews takes the opposite approach – and the results are remarkable.
In this TEDx-proven keynote, Lindsy introduces a counterintuitive framework: using the perspective of our future selves as a lens to dramatically shift how we experience the current moment. When we mentally inhabit who we will be – rather than who we are under pressure right now – our relationship to stress, adversity, and even everyday decisions changes completely.
Drawing on research in psychology and her own experience of navigating life with Stage 4 cancer, Lindsy shows audiences how to access a calmer, wiser, longer-range point of view when they need it most. The result is a practical mindset tool that reduces reactive decision-making, improves perspective under pressure, and brings surprising clarity to both professional and personal challenges.
Audiences leave with a technique they can use the same day – and that becomes more powerful the more they practice it.
This is not a talk about the future. It’s a talk about right now – seen through a lens that makes right now much more manageable.
Ideal for: corporate leadership events, executive teams, professional development days, financial and technology organizations, and any audience facing rapid change or high-pressure decision-making.
Suggested Length: 45-60 minutes (including 15 minutes Q&A)
Keynote #3
Antifragile: Building Teams That Grow Stronger Under Pressure
Resilient teams survive disruption. Antifragile teams are shaped and strengthened by it. There’s a significant difference – and the gap between them is leadership.
In this high-energy, practical keynote, Lindsy Matthews introduces the concept of antifragility and translates it from theory into concrete strategies that leaders and teams can begin applying immediately. Drawing on her experience working with corporate organizations and her own remarkable journey of building a thriving career while living with a life-limiting diagnosis, Lindsy makes the case that our greatest periods of growth rarely arrive when things are going well – they arrive when things fall apart.
Audiences leave with a clear framework for identifying fragility in their teams and systems, practical habits for building psychological safety under pressure, and a renewed understanding that adversity, handled well, is not an obstacle to peak performance – it is the path to it.
This keynote is especially powerful for organizations navigating rapid change, industry disruption, restructuring, or the ongoing challenge of retaining and energizing talent in uncertain times.
Ideal for: financial institutions, technology companies, executive leadership conferences, HR and people & culture events, and any organization that wants teams who don’t just cope with change – they lead through it.
Suggested Length: 45-60 minutes (including 15 minutes Q&A)
Keynote #4
The Patient Perspective: Raising Awareness and Advocacy for Stage 4 Metastatic Breast Cancer
In this keynote, Lindsy looks deeper into the lesser known implications and impact of stage 4, incurable and terminal metastatic breast cancer has on individuals, families and society as a whole. With an emphasis on raising awareness and inspiring advocacy, Lindsy aims to ignite a transformative dialogue that brings forth meaningful change in how we approach this devastating disease.
Learning Outcomes:
- Heightened Awareness: Gain a deep understanding of stage 4 metastatic breast cancer, including its progression, unique characteristics, and its impact on individuals and their loved ones.
- Empowered Advocacy: Discover the power of advocacy in creating positive change for individuals with stage 4 metastatic breast cancer. Learn effective strategies to raise awareness, influence public opinion, and advocate for improved policies, increased research funding, and equitable access to treatment and support services.
- Comprehensive Support Systems: Explore the importance of holistic support systems for individuals with stage 4 metastatic breast cancer. Discover practical ways to enhance the quality of life for patients and their families, including strategies for self-care, and emotional support.
- Shifting Narratives: Challenge preconceived notions and stigmas surrounding metastatic breast cancer, promoting a shift in public perceptions from one of hopelessness to one of resilience and empowerment.
Suggested Length: 45-60 minutes (including 15 minutes Q&A)


